CAD - Coronary Artery Disease

Background

Coronary artery disease (CAD) is a condition in which the arteries that supply blood to the heart itself become narrowed or blocked due to a buildup of plaque. This plaque is made of cholesterol, fat, and other substances that stick to the artery walls.

As the arteries narrow, less oxygen-rich blood reaches the heart muscle. This can cause chest pain, shortness of breath, or even a heart attack. CAD is the most common form of heart disease and
a major cause of death globally.

CAD In Numbers

200M+

People worldwide live with CAD

40 Seconds

Someone in the US has a heart attack

15%

Of all hospitalizations in the US are due to CAD

50%

Of heart attacks occur without prior warning

1/3

Of US deaths over age 35 are caused by CAD

80%

Of cardiovascular-related deaths are linked to modifiable risk factors

A man holding his chest

Diagnostic Gaps And Failures

Current diagnostic tools often detect CAD at advanced stages, missing opportunities for early intervention

90% of AMI patients have significant CAD

Only 50% of patients sent for coronary angiography require treatment

Black, Hispanic, and Native Americans experience disproportionately high rates of CAD

Chart on screen

Economic Burden Of CAD

The average cardiac event costs $50,000 in immediate care

First-year medical costs after a heart attack range from $50,000 to $87,000 per patient

Lifetime treatment of heart attack patients in the US can reach $1 million

CAD imposes a major burden on the US healthcare system, with annual costs exceeding $220 billion

The Unmet Need - Point Of Care Exam For CAD

Chest pain is the most common complaint at US PCP clinics – around 3M annually

Only 15% of patients with chest pain have CAD

Neither PCPs nor cardiologists have a point-of-care exam to determine whether the patient has significant CAD

An old couple in the hospital

Due to its life-risking nature, nearly all chest pain patients are referred for further examination

Many are referred to a cardiologist – yet nearly 50% of counties in the US do not have one

The frontline exams – stress tests – are not accurate enough, this leads to:

  • Wasted billions in downstream testing
  • Diagnostic gap – current tests miss many positive patients.

The Problem - Stress Test Fall Short

  • Inaccurate – misdiagnosis of at-risk, over diagnosis of healthy
  • Delayed care for true cardiac patients
  • Time consuming
  • Capital and labor-intensive
  • Require physical exercise
  • Long referral times
  • Radiation exposure
Stress test

The Solution - AI At The Point Of Care

Enables early and accurate detection

Closes gaps in preventive care and slows disease progression

Supports life changes that reduce morbidity and mortality